Authored by: Dr. Juan Chavez, MD and Dr. Lucia Mireles-Chavez, MD
The P-Shot, or Priapus Shot, has become a popular topic among men searching for natural, regenerative solutions to improve erectile function and sexual confidence. Using platelet-rich plasma (PRP) derived from a patient’s own blood. This non-surgical treatment is designed to enhance blood flow, repair tissue, and stimulate cellular regeneration within the penis.
For men exploring alternatives to medications, understanding the true success rate of the P-Shot is essential. This treatment may provide mild to moderate improvement, particularly for those with early-stage erectile dysfunction, but results vary widely. Here’s what current research and patient experience reveal about how well the P-Shot works, who benefits most, and what to expect from this evolving approach in men’s sexual health.
The P-Shot, short for Priapus Shot, is a non-surgical treatment designed to address male sexual dysfunction, especially erectile dysfunction. It falls under the broader umbrella of regenerative medicine therapies that leverage the body's own healing capacity.
At its core, the P-Shot involves extracting a small blood sample from the patient, processing it to isolate platelet rich plasma (PRP), and then injecting the PRP into specific areas of the penile tissue. The main goal is to improve erectile function by stimulating tissue regeneration and enhancing blood flow.
The interest in the P-Shot largely centers on its reported ability to address common issues like poor sexual performance, reduced penile blood flow, and challenges with sexual intercourse in patients with erectile dysfunction.
PRP is a concentrated solution of platelets sourced from a patient's own blood. This element is packed with growth factors, including vascular endothelial growth factor and platelet derived growth factor, which are believed to help repair tissues and promote new blood vessel formation. By introducing PRP directly into penile tissue, practitioners hope to boost natural healing and improve sexual function.
Understanding the P-Shot procedure helps clarify what patients can expect from this treatment modality for erectile dysfunction.
First, a healthcare provider takes a small blood sample, typically from the patient's arm. This sample is processed using a centrifuge to separate and concentrate the platelets, resulting in PRP. Before injection, a numbing cream is applied to the penis to minimize discomfort at the injection site.
The resulting platelet rich plasma is then carefully injected into targeted areas of the penis. The procedure usually takes under an hour, and most patients can return to normal activities soon after.
The science behind the P-Shot centers on delivering a high concentration of growth factors directly to penile tissue. These growth factors, such as insulin like growth factor and vascular endothelial growth factor, can, in theory, accelerate wound healing, encourage the formation of new blood vessels, and aid in tissue regeneration. Improved blood flow is thought to support improved erectile function. But, clinical trials are still ongoing to determine whether these mechanisms reliably translate into real-world benefits for ED patients.
Platelet rich plasma therapy has also been explored for other male sexual health concerns, such as Peyronie's disease and severe ED that does not respond to conventional oral medications or hormone therapy.
Several key factors can influence the success rate of the Priapus Shot for treating ED patients.
The greatest improvements with the P-Shot have typically been observed in men with mild erectile dysfunction. Those with more severe ED, long-standing conditions, or complex medical histories (such as diabetes mellitus or cardiovascular disease) are less likely to see statistically significant benefit. Vascular causes of ED, like reduced penile blood flow, may respond somewhat betterl.
Inclusion criteria vary widely across clinics and studies, making broad generalizations difficult. Men who have not responded to first-line treatment options or who have contraindications to oral ED drugs might consider PRP treatment as a next step, but only after thorough consultation. Patient expectations, underlying conditions, and concurrent therapies (like hormone therapy or phosphodiesterase inhibitors) all play a role.
The P-Shot procedure isn't standardized across clinics. Success may depend on variations in the preparation of platelet rich plasma, the concentration of growth factors, and the injection technique utilized. Also, some practitioners combine PRP with shockwave therapy in experimental protocols, though these approaches lack robust data at present.
Variables like how many P-Shots a patient undergoes and the interval between procedures may also affect long-term outcomes. Most studies to date have used a single PRP injection, while anecdotal reports sometimes mention better results with a series of treatments.
Patients' reports on the P-Shot's effectiveness provide a nuanced picture that complements the formal clinical data.
Many men describe improvements in overall sexual health, confidence, and, in some cases, increased ability to achieve or maintain an erection. In surveys and small observational studies, some men with mild or medication-resistant ED report modest benefit and improved sex life.
The P-Shot is generally well tolerated. Most men rate the pain associated with PRP injections between 3.5 and 4 out of 10. This mild to moderate discomfort is often managed with topical numbing cream. Minor side effects such as temporary pain, mild swelling, or slight bruising at the injection site can occur, but major or serious adverse events are rare according to published clinical studies.
For those with realistic expectations, the P-Shot may provide a non-surgical, low-complication avenue to potentially improve erectile function.
Randomized clinical trials have shown that about 58% of men who received the P-Shot achieved a clinically difference at six months, compared to 54% in the placebo group.
Current research indicates the P-Shot is generally safe, with most side effects being minor and short-term, such as mild pain or swelling at the injection site. Serious adverse events are rare when the procedure is performed in a qualified clinical setting.
Men with mild erectile dysfunction or those who have not responded to traditional treatments may see the most benefit. However, results vary and men with severe ED, long-term conditions, or significant underlying health issues are less likely to experience improvement.
The P-Shot is not primarily designed for permanent penile enlargement. Some men report a slight increase in girth or firmness due to improved blood flow and tissue health. The main goal of the treatment is to enhance erectile function and sensitivity rather than create permanent size changes.
Most men start with one P-Shot treatment to address erectile dysfunction, but results can differ depending on the severity of the condition. Some patients benefit from a series of two to three sessions spaced several months apart for more consistent results. Maintenance treatments may also be recommended annually to sustain improvement.
The P-Shot typically costs between $1,000 and $2,000 per treatment in Fresno, California. The Optimal Medical Group offers flexible financing options to make the procedure more accessible for patients seeking improved sexual performance and confidence.
Current research shows that the P-Shot is generally safe and well-tolerated, offering promising potential for men seeking a natural, regenerative approach to improve sexual health. Many men, especially those with mild erectile dysfunction, report modest improvements in performance, sensitivity, and confidence.
Patients considering the P-Shot are encouraged to discuss all available treatment options with a qualified specialist and set realistic expectations based on their individual health goals. As regenerative medicine continues to advance, ongoing research may further enhance the procedure’s effectiveness and help identify those who benefit most. For men interested in exploring a cutting-edge, low-risk therapy for better sexual wellness, the P-Shot remains a worthwhile option under expert medical guidance.
Enhance Performance. Increase Size. Restore Confidence.
Unlike pills or pumps that offer temporary fixes, the Priapus Shot (P-Shot) uses your body's own platelet-rich plasma (PRP) to naturally regenerate tissue and increase blood flow where it matters most. It's like hitting the reset button on your sexual vitality using your body's own healing power.
This isn't your typical performance solution. Our advanced PRP injection technique stimulates new tissue growth, improves circulation, and enhances sensation for results that last months, not hours.
Experience Benefits You Can Actually SEE and FEEL:
Why settle for temporary pills when you can have lasting results? The P-Shot uses proven regenerative medicine that thousands of men trust to restore their sexual confidence. Many patients report improvements they haven't felt in years after just one treatment.
At Optimal Medical Group, we combine advanced PRP technology with discreet medical expertise for results that transform your intimate life.
Schedule Your P-Shot Consultation here, or call us today at (559) 840-0066 and discover how the P-Shot is helping men regain their confidence and perform at their peak in Fresno!
Cover Photo Illustration by: By the Optimal Medical Group.
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