Authored by: Dr. Juan Chavez, MD and Dr. Lucia Mireles-Chavez, MD
Does the P-Shot Work? For some men, especially those with mild to moderate ED, platelet rich plasma (PRP) injections like the P-Shot have shown potential to improve erectile function and sexual health. PRP therapy involves injecting growth factors from your own blood directly into penile tissues to stimulate blood flow, tissue repair, and possibly boost sexual function.
Clinical trials find that a subset of men notice real improvements in erectile function scores and sexual satisfaction within a few weeks. With years of experience in men's sexual health and in-depth review of scientific evidence, and patient-reported results, this article delivers up-to-date, unbiased answers.
The P-Shot, or Priapus Shot, is a non-surgical treatment option for men's sexual health concerns, especially erectile dysfunction. It's based on the use of platelet-rich plasma (PRP), which is derived from a man's own blood sample.
Platelet-rich plasma therapy takes a blood draw and spins it in a centrifuge to concentrate the platelets and growth factors while separating out red blood cells and platelet poor plasma. What remains is a yellowish serum rich in proteins that help with wound healing and tissue growth. This PRP is carefully injected into specific penile tissues under the supervision of a healthcare provider.
In sexual medicine, the P-Shot is promoted as a way to enhance sexual function by improving blood circulation, promoting new blood vessels, and rejuvenating penile tissues.
It's sometimes considered for men dealing with moderate ED, male sexual dysfunction after prostate surgery, Peyronie's disease, or even premature ejaculation. But, the main marketing aim remains improving erections, sensation, and overall sexual satisfaction in a clinical setting.
The promise behind the P-Shot lies in using your own blood components to promote healing within the penis. But how exactly do these platelet rich plasma injections aim to treat erectile dysfunction and related concerns?
Inside PRP are growth factors, special proteins that trigger the body's own repair processes. When injected into the penis, these growth factors are theorized to:
The procedure begins with a local anesthetic (often a numbing cream) to minimize discomfort. After drawing blood, the PRP is prepared and injected at several penile injection sites.
The goal: Improve blood flow and potentially enhance erectile function over time, typically within a few weeks. Some clinics combine PRP with other treatments, like a vacuum erection device or oral medications, but the core claim focuses on PRP's ability to promote tissue growth and improve sexual function on its own.
Research into whether the P-Shot works is rapidly growing, but remains far from definitive. Some placebo controlled clinical trials and systematic reviews have tested PRP injections for mild to moderate ED.
One key double-blind clinical trial found that 69% of men who received PRP injections met the minimal clinically important difference in erectile function scores compared to just 27% in the placebo group. This suggests a real benefit in some men, particularly those with vascular, mild to moderate ED. No major adverse effects over six months were reported.
Other studies, but, paint a more mixed picture. Several randomized controlled trials and meta-analyses show that while some men experience improved erectile function, others see little difference compared to placebo. Major sexual medicine organizations note that sample sizes are small and follow-up periods short, making it difficult to generalize results to all men dealing with sexual dysfunction.
A recurring theme in the literature is the need for more high quality research. Many studies lack standardized protocols for PRP preparation, injection sites, and outcome measures.
For those with severe erectile dysfunction or complex health histories (such as advanced prostate cancer or severe Peyronie's disease), results are even less clear. Most experts advise that PRP remains experimental until larger, longer-term trials clarify who benefits, and who does not.
So what can eligible patients reasonably expect? While not a miracle cure, the P-Shot does offer documented benefits for select men.
In clinical practice and trials, men with mild to moderate ED often report stronger or more reliable erections after PRP injections. Some describe increased blood flow, better tissue response, and improved confidence during sexual activity.
Satisfaction rates are higher in certain studies, even when objective improvement in erectile function is modest. PRP may also help men experiencing penile pain or mild curvature from Peyronie's disease by promoting tissue healing and reducing scar tissue buildup.
Most clinicians and studies note that benefits tend to appear within a few weeks post-procedure, though results vary. Some men require multiple P-Shot treatments for maximal effect. Lasting improvements by three to six months have been reported, but many men only see moderate changes.
It's important to remember that the P-Shot likely works best in combination with other treatments (such as oral medications or vacuum erection devices), rather than as a standalone solution for moderate ED.
While the P-Shot treatment is promoted as a safe, minimally invasive procedure, men considering this treatment should be aware of the potential risks.
Most studies report side effects as mild and temporary. Short-lived discomfort at the injection site, mild penile pain, bruising, or minor hematoma are most common.
Rarely, the p-shot injection process could aggravate pre-existing plaque or scar tissue, especially in cases of Peyronie's disease. No major long-term adverse effects have been confirmed, but monitoring is ongoing.
Because PRP is derived from your own blood, allergic reactions are rare. Still, the long-term safety of repeated PRP injections into penile tissues hasn't been firmly established.
Experts caution that, while the procedure is generally low risk under medical supervision, the true long-term risks may not emerge until larger placebo-controlled clinical trials are completed. Men should avoid seeking the P-Shot from unverified or unlicensed providers, as technique and product quality can affect safety and results.
Ideal candidates for the P-Shot share some key traits, and not every man seeking improved sexual function will be a good fit.
The most promising results have been seen in men with mild to moderate erectile dysfunction, often of vascular origin. For these men, PRP injections may offer another option when oral medications are ineffective or cause side effects.
Men recovering from prostate surgery or those with conditions that restrict blood flow to the penis (but who still maintain some erectile function) might also benefit.
Men with severe ED, extensive nerve damage, advanced prostate cancer, or significant structural problems (as from major Peyronie's disease) should temper expectations. For these groups, the evidence is weaker, and better-established therapies take priority.
It's essential to speak with a healthcare provider to review medical history, underlying causes, and possible interactions with other treatments.
Understanding what happens during a P-Shot appointment helps set realistic expectations and minimizes anxiety.
A certified healthcare provider or medical director will review your medical history and confirm you're a candidate. The procedure generally takes under 30 minutes. After a quick blood draw from your arm, your blood sample is spun in a centrifuge to prepare platelet rich plasma.
The penis is numbed with a cream or local anesthetic to ensure comfort. Using a fine needle, the clinician makes a series of PRP injections at set penile injection sites. Most men describe the discomfort as mild, especially with proper numbing.
Patients usually return to normal activities within hours. Some minor soreness or bruising can occur, but this generally fades quickly. Sexual activity can often resume within a day or two, but always follow your clinic's specific guidance.
Multiple treatments may be recommended, with progress reviewed after each session. The full course and cost may vary, so ask your clinic about package options and best practices based on your needs.
Early studies suggest the P-Shot may moderately improve erectile function in some men, especially those with mild to moderate ED. However, the evidence is limited and mixed, so it shouldn’t replace established ED treatments. More rigorous research is needed to confirm its effectiveness.
The P-Shot uses platelet-rich plasma (PRP) from the patient’s own blood, injected into the penis to stimulate tissue repair, blood flow, and potentially nerve regeneration. Growth factors in PRP are thought to promote healing and improve erectile function, though results vary.
Some men report improved erection quality, sexual satisfaction, and blood flow a few weeks after treatment. Risks are usually mild, such as swelling or bruising. Serious complications are rare, but long-term safety data is lacking and more research is needed.
Men with mild to moderate erectile dysfunction who have not responded to oral medications may consider the P-Shot, especially within clinical trials. It’s important to have a medical evaluation to determine if this treatment is appropriate for your health status.
No. Leading medical associations regard the P-Shot as experimental and do not recommend it as a mainstream treatment for erectile dysfunction at this time. It should only be considered after consulting a qualified healthcare provider.
Some men notice improvements in erection quality within a few weeks of receiving the P-Shot. However, the effects are typically moderate and not permanent. Results may diminish over time and additional treatments may be necessary.
Current scientific evidence suggests that the P-Shot, or Priapus Shot, offers potential benefits for men with mild to moderate erectile dysfunction. For those who are not fully satisfied with oral tablets or other standard treatments. The benefits men report are improved erectile function, sensation, and sexual satisfaction within a few weeks of PRP injections.
For now, respected urology and sexual medicine experts advise that men view the P-Shot as an adjunct, not a replacement, for evidence-based ED treatments. If you’re interested, schedule a consultation and begin enjoying the benefits this treatment can offer. The future of PRP therapy for men's sexual health is promising, but not yet fully realized.
Enhance Performance. Increase Size. Restore Confidence.
Unlike pills or pumps that offer temporary fixes, the Priapus Shot (P-Shot) uses your body's own platelet-rich plasma (PRP) to naturally regenerate tissue and increase blood flow where it matters most. It's like hitting the reset button on your sexual vitality using your body's own healing power.
This isn't your typical performance solution. Our advanced PRP injection technique stimulates new tissue growth, improves circulation, and enhances sensation for results that last months, not hours.
Experience Benefits You Can Actually SEE and FEEL:
Why settle for temporary pills when you can have lasting results? The P-Shot uses proven regenerative medicine that thousands of men trust to restore their sexual confidence. Many patients report improvements they haven't felt in years after just one treatment.
At Optimal Medical Group, we combine advanced PRP technology with discreet medical expertise for results that transform your intimate life.
Schedule Your P-Shot Consultation here, or call us today at (559) 840-0066 and discover how the P-Shot is helping men regain their confidence and perform at their peak in Fresno!
Cover Image Credit: Mklrnt / 123RF.com (Licensed). Photo Illustration by: The Optimal Medical Group.
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